Maria A. Guglielmo,
M.D.
Telephone: (401)739-4988
Licensure_______________________________________________________________
ABNS
Board Certification, May 2003
RI
License: MD11912
NH
License: 12458
WA
License: MD00037407
Employment____________________________________________________________
2005-present Founder, Ocean State
Neurosurgery, LLC
2005-present Medical Director of Neurosurgery,
2004-2005
Physician,
1999-2004
Senior
Physician, Department of Neurosurgery, Northwest
Permanente, P.C., Physicians and Surgeons
97105, August 1999-September 2004
Education_______________________________________________________________
1993-1999
Resident,
Program in Neurosurgical Surgery,
1992-1993
Surgical
Internship,
1988-1992
M.D.,
1984-1988
B.S. in
Biology,
Honors
and Awards_______________________________________________________
2000
Kaiser
Permanente James A. Vohs Award, Quality for the North-
west Integrated Pain Management Program
1992 Patricia McCormick
Prize for Outstanding Achievement, Brown
1992
1988 Cum Laude Graduate,
1987-1988
Quonset Point
Management Scholarship,
Publications,
Articles_____________________________________________________
M.A.
Guglielmo, P.T. Chan, S. Cortez, E.G. Stopa, P. McMillan, C.E. Johansen, M. Epstein and C.E. Doberstein: “The Temporal Profile and Morphologic Features
of Neuronal Death in Human Stroke Resemble Those Observed in Experimental
Forebrain Ischemia: The Potential Role of Apoptosis”, Neurological Research, 20:1998.
M.A.
Guglielmo, R. Ridzon:
“Frontal Sinusitis Causing a Fatal Brain Abscess”, Emergency Medicine and Acute Primary Care, vol. 166(121), August
1997.
M.A.
Guglielmo and C. Doberstein,
“Vascular Malformations” in Prognosis in Neurology, J. Gilchrist, ed.,
Butterworth-Heinemann:
M.A.
Guglielmo and C. Doberstein,
M.D., “Concurrent Rupture of an Intracranial and Mesenteric Aneurysm: A Case
Report”. Journal of
Neurovascular Disease, Vol.3, No.1, pp 27-30, 1998.
D.E.
Palm, N. Knuckey, M. Guglielmo,
P. Watson, M. Primiano, C. Johansen: “Temporal
Profile of Electrolyte and Ultrastructural Changes in
the Choroid Plexus Following Transient Forebrain
Ischemia”, Amer J. Physiol.,
269: R73-R79, 1992.
D.E.
Palm, P. Watson, J. Osborne, M. Guglielmo, C.
Johansen, N. Knuckey: “Effects of Acute Transient
Ischemia on Choroid Plexus Function and Structure”. FASEB Abstracts, 6:A1062, 1992.
M.J.
Tramo, M.A. Guglielmo, P.
Reuter-Lorenz, M. Gazzaniga:
“Left Hemi-spatial Neglect: Quantitative Cortical Mapping and Recovery
Patterns”. Annals of Neurology,
28:255A, 1990.
Presentations____________________________________________________________
M.
Guglielmo, P. Chan, M. Mittler,
C. Johansen, M. Epstein, and C. Doberstein: Intraventricular Infusion of bFGF
and Neuronal Apoptosis Following Transient Forebrain Ischemia in Rat
Hippocampus, AANS Cerebrovascular
Section Meeting, Orlando, FL, 1998.
M.
Guglielmo, P. Chan, C. Doberstein,
C. Johansen, and M. Epstein: A Comparative Analysis of Neuronal Cell Death in
Decapitation Necrosis and Transient Forebrain Ischemia in the Rat, Society for Neuroscience, New Orleans,
LA, 1997.
F.
Harrington, M. Guglielmo, P. Chan: The Role of
Apoptosis in the First Twelve Hours after Experimental Acute Spinal Cord
Injury, AANS/CNS Section on Spine and
Peripheral Nerves, Newport Beach, CA, February 1997.
M.
Guglielmo, P. Chan, C. Doberstein,
and C. Johansen: TUNEL and ISEL Histochemistry in
Experimental Rat Models of Forebrain Ischemia and Necrosis, Brown University/Rhode
J.
Teng, M. Guglielmo, P.
Chan, D. Palm, V. Kuo-Leblanc, S. Cortez, C.
Johansen, E. Stopa: Cystatin
C Immunoreactivity in Anterior Horn Cells in ALS
Patients, Brown Brain Science Research
Day, 1997.
M.
Guglielmo, P. Chan, C. Doberstein,
S. Cortez, E. Stopa, N. Knuckey,
C. Johansen and M. Epstein: A Comparative Temporal and Morphologic Analysis of
Delayed Neuronal Death Following Experimental Transient Forebrain Ischemia in
Rat and Human Stroke, Brown Brain Science
Research Day, 1997.
C.
Doberstein, M. Guglielmo,
P. Chan, D. Demers, M. Primiano, D. Palm, N. Knuckey, C. Johansen and M. Epstein: Temporal Profile of
TUNEL Histochemistry Following Transient Forebrain
Ischemia in the Rat, Brown Brain Science
Research Day, 1997
P.
Chan, M. Guglielmo, C. Doberstein,
V. Kuo-LeBlanc, E. Stopa,
N. Knuckey, C. Johansen and M. Epstein: TUNEL Histochemistry
and bFGF Expression in Ischemic Rat Hippocampus, Brown Brain Science Research Day, 1997.
P.
Chan, M. Guglielmo, Y. Kang, N. Knuckey,
D. Palm, M. Primiano, C. Johansen: Tumor Necrosis
Factor Alpha in Rat Hippocampus and Neocortex
Following Transient Forebrain Ischemia, Brown
Brain Science Research Day, 1997.
M.
Guglielmo, P. Chan, C. Doberstein,
S. Cortex, D. Demers, N. Knuckey, C. Johansen and M.
Epstein: Evidence for Apoptotic Cell Death Following Ischemia in an
Experimental Model and Human Brain Specimens, Congress of Neurosurgical
Surgeons, 1996.
M.
Guglielmo, P. Chan, C. Doberstein,
D. Demers, M. Primiano, D. Palm, N. Knuckey, C. Johansen and M. Epstein: The Temporal Expression of bFGF and Neuronal Apoptosis Following Transient Forebrain
Ischemia in Rat Hippocampus, Congress of
Neurosurgical Surgeons, Montreal, Canada, 1996.
M.
Guglielmo, P. Chan, C. Doberstein,
D. Demers, M. Primiano, D. Palm, N. Knuckey, C. Johansen and M. Epstein: Delayed Neuronal Death
Following Transient Forebrain Ischemia in Rat Hippocampus: A Comprehensive
Temporal Analysis, Society for
Neuroscience, Washington, D.C., 1996.
J.
Teng, M. Guglielmo, P.
Chan, V. Kuo-Leblanc, S. Cortez, C. Johansen, E. Stopa: Evidence Against Programmed Cell Death in
Amyotrophic Lateral Sclerosis, Brown
University/Rhode Island Hospital Research Day, 1996.
N.
Knuckey, M. Primiano, D.E.
Palm, M. Guglielmo, M. Epstein, C. Johansen: The
Distribution of bcl-2 Protein in the Rat Hippocampus Following Transient
Forebrain Ischemia, Society for
Neuroscience, San Diego, CA, 1995.
Teaching
and Committees_________________________________________________
2000-2004
Subspecialty
Representative, Kaiser Permanente Pain Board
1996-1997
Faculty
Instructor, Brain Attack Curriculum
1996-1998 Consulting
Lecturer/Instructor,
Course
1997
Consulting
Lecturer/Instructor,
Course,
1995-1997
Resident
Representative, RI Hospital, Critical Path Planning
Committee
1996
Consulting
Lecturer/Instructor, Advanced Trauma Life Support
Curriculum,
1991-1992
Surgical
Assistant,
1991-1992
Tutor, NBME
Review Course,
1989-1990
Academic
Tutor, Anatomy,
NH
1985-1988
Freshman
Counselor,
Research
Appointments and Grants_________________________________________
1995-1997
Principal
Researcher, Ischemia and Trauma Group, Brown Univer-
sity/Rhode
1996-1997
Principal
Researcher, “Characterization of temporal expression and
functional role of p53, bcl-2 bax
and ICE in ischemia-induced apoptic cell death” NIH
Grant #: NS27601, Rhode Island Hospital Developmental Grant #7742
1996-1997 Principal Researcher,
“Programmed cell death following traumatic brain injury”, Rhode Island
Foundation Grant #7960
1996-1997
Principal
Researcher, “Characterization of HO-1, Cystatin C and
TUNEL staining in ALS”, Dana Barrengos
ALS Foundation Grant
1989-1990
NIH Summer
Scholar,
science
1985-1988
Research
Assistant, Yale Dept. of Biology,
Laboratory
Research______________________________________________________
1995-1997
“ The role of
apoptosis and growth factors in transient forebrain
ischemia”
Brown University/Rhode
Neurosciences, Neurosurgery Research
1995-1997
“The role of
apoptosis and growth factors in traumatic brain injury
in the rat”
Brown University/Rhode
Neurosciences, Neurosurgery Research
1995-1997
“The role of
apoptosis in human stroke”
Brown University/Rhode
Neurosciences, Neurosurgery Research and Rhode
Island Hospital Department of Pathology, Neuropathology Division
1995-1997
“Cell death
in ALS”
Brown University/Rhode
Neurosciences, Neurosurgery Research and Rhode
Island Hospital Department of Pathology, Neuropathology Division
1989-1990
“A computer
model of quantitative cortical mapping in neurologic
disease”
Department of Cognitive Neuroscience,
1985-1988
“CNS
morphology in Drosophila mutants”
Yale University Department of Biology